Propargyl-PEG12-OH


CAS No. : 1036204-61-1

1036204-61-1
Price and Availability of CAS No. : 1036204-61-1
Size Price Stock
100mg $75 In-stock
250mg $138 In-stock
500mg $213 In-stock
1g $317 In-stock
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Cat. No. : HY-117045
M.Wt: 584.69
Formula: C27H52O13
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1036204-61-1 :

Propargyl-PEG12-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG12-OH is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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