Valiltramiprosate
CAS No. : 1034190-08-3
(Synonyms: ALZ-801)
| Size | Price | Stock |
|---|---|---|
| 5mg | $110 | In-stock |
| 10mg | $190 | In-stock |
| 25mg | $420 | In-stock |
| 50mg | $625 | In-stock |
| 100mg | $900 | In-stock |
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| Cat. No. : | HY-117259 |
| M.Wt: | 238.30 |
| Formula: | C8H18N2O4S |
| Purity: | >98 % |
| Solubility: | H2O : 30 mg/mL (ultrasonic;warming;heat to 60°C) |
ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, valine-conjugated prodrug of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound[1]. ALZ-801 is an advanced and markedly improved candidate for the treatment of alzheimer’s disease[2]. IC50 & Target:β-amyloid[1] In Vivo: ALZ-801 (oral administration; 172 mg/kg; single dose) exhibits mean AUCt values of 58,758 and 5841 ng/ml.h in plasma and brain, respectively. The ALZ-801: Tramiprosate ratio in plasma and brain is 1.8 and 3.1, respectively in male CD-1 mice[1].
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