MK-7725


CAS No. : 1034152-93-6

1034152-93-6
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Cat. No. : HY-18612
M.Wt: 615.50
Formula: C25H19F6N5O5S
Purity: >98 %
Solubility:
Introduction of 1034152-93-6 :

MK-7725 is a selective, orally active, and blood-brain barrier-permeable agonist of the subtype 3 of the frog skin peptide receptor (BRS-3). MK-7725 has a high affinity for the human BRS-3 (hBRS-3), with an IC50 of 3 nM, and its functional activity in the mouse-derived BRS-3 (mBRS-3) model with an EC50 of 22 nM (105% agonistic). MK-7725 significantly reduces the body weight of obese rats and obese dogs. MK-7725 can be used for the treatment of obesity[1].

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