N-Methylisatoic anhydride


CAS No. : 10328-92-4

10328-92-4
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Cat. No. : HY-18407
M.Wt: 177.16
Formula: C9H7NO3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 10328-92-4 :

N-Methylisatoic anhydride is a heteronucleoside anhydride derivative conjugated with biotin and a disulfide linker for specific 2'-OH acylation of RNA. Biotin-conjugated N-Methylisatoic anhydride can selectively capture RNA from a mixture of biological RNA and DNA[1]. In Vitro:N-Methylisatoic anhydride is a 20-OH selective acylation agents of RNAs, and widely used for resolving secondary RNA structures using the SHAPE (Selective 20-Hydroxyl Acylation Analyzed by Primer Extension) technology[1].

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