L 655240
CAS No. : 103253-15-2
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| Cat. No. : | HY-108564 |
| M.Wt: | 373.85 |
| Formula: | C21H21ClFNO2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
L 655240 is thromboxane antagonist. L 655240 attenuates early ischemia- and reperfusion-induced arrhythmias in a canine model of coronary artery occlusion. L 655240 also involves in cancer and autoimmune disorders[1].
In Vitro:L 655240 (7 nM) inhibits endoperoxide-induced aggregation in human paltelets[1].
In Vivo:L 655240 (0.3 mg/kg; i.v.; single dose) changes heat rate, arterial and pulmonary arterial blood pressure, and cardiac output in canine model[1].
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