MTL-005
CAS No. : 1030303-53-7
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| Cat. No. : | HY-19938 |
| M.Wt: | 958.54 |
| Formula: | C38H42B20CuN6O6 |
| Purity: | >98 % |
| Solubility: |
MTL-005 is a boron-containing radiosensitizer used in Boron Neutron Capture Therapy (BNCT). MTL-005 enriches the boron-10 isotope in tumor tissues, causing nuclear fission under thermal neutron irradiation, releasing high linear energy transfer (LET) α particles and lithium ions, which selectively destroy tumor cells while minimizing damage to surrounding normal tissues. MTL-005 significantly controlls the tumor progression in the SCCVII squamous cell carcinoma mouse model and prolonged the survival of the mice. MTL-005 can be used to study solid tumors such as head and neck cancer.
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- MTL-005
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