| Size | Price | Stock |
|---|---|---|
| 10g | $19 | In-stock |
| 100g | $95 | In-stock |
| 500g | $278 | In-stock |
| 1 kg | Get quote | |
| 2 kg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-Y0351 |
| M.Wt: | 152.22 |
| Formula: | C7H8N2S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Phenylthiourea (Phenylthiocarbamide) is an inhibitor for phenoloxidase. Phenylthiourea inhibits enzymatic oxidation of DOPA by phenoloxidase (Ki = 0.21 μM). Phenylthiourea is an effective inhibitor for tyrosinase. Phenylthiourea can lead to graying of hair in black rats due to the interference with melanin formation[1][2].
IC50 & Target:phenoloxidase[1]
In Vitro:Phenylthiourea (Compound PTU) (0-20 μM, 0-300 s) affects the melanization process by either inhibiting the action of phenoloxidase directly or reducing DOPA-quinine to DOPA[1].
Phenylthiourea (0-2.5 μM) has inhibitory effect on DOPA oxidation catalyzed by phenoloxidase (Ki = 0.21 μM)[1].
Phenylthiourea (Compound Phenylthiocarbamide) inhibits the methemoglobin production in rat tissues[2].
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