Moracin P
CAS No. : 102841-46-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $250 | In-stock |
| 10mg | $410 | In-stock |
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| Cat. No. : | HY-N3243 |
| M.Wt: | 326.34 |
| Formula: | C19H18O5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects[1][2][3]. In Vitro: Moracin P enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC50 value of 10.4 μM. Moracin P reduces ROS production in OGD-induced cell death (IC50 values of 1.9 μM). Consequently, reactive oxygen species (ROS) are overexpressed in OGD-induced cells and Moracin P reduces ROS induced by OGD in dosedependent manner[1].
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