Dactolisib (Tosylate) (Standard)
CAS No. : 1028385-32-1
(Synonyms: BEZ235 (Tosylate) (Standard); NVP-BEZ 235 (Tosylate) (Standard))
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| Cat. No. : | HY-15174R |
| M.Wt: | 641.74 |
| Formula: | C37H31N5O4S |
| Purity: | >98 % |
| Solubility: |
Dactolisib (Tosylate) (Standard) is the analytical standard of Dactolisib (Tosylate). This product is intended for research and analytical applications. Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively. Dactolisib Tosylate (BEZ235 Tosylate) inhibits mTORC1 and mTORC2.
IC50 & Target:IC50: 4nM (PI3Kα), 75 nM (PI3Kβ), 7 nM (PI3Kγ), 5 nM (PI3Kδ)[1]
mTORC1, mTORC2[1]
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