VUF10460
CAS No. : 1028327-66-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $66 | In-stock |
| 10mg | $110 | In-stock |
| 25mg | $220 | In-stock |
| 50mg | $385 | In-stock |
| 100mg | $605 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-101420 |
| M.Wt: | 269.34 |
| Formula: | C15H19N5 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
VUF10460 is a non-imidazole histamine H4 receptor agonist; binds to rat H4 receptor with a pKi of 7.46. IC50 & Target: pKi: 7.46 (H4)[1] In Vitro: UF10460 binds to rat H3 and H4 receptor with pKi values of 5.75, and 7.46, respectively. VUF10460 displays approximately a 50-fold selectivity for the rat H4 receptor over the H3 receptor[1]. In Vivo: HCl-induced rat gastric lesions is significantly enhanced by the H4 receptor agonists VUF10460. This effect is not modified by H4 receptor antagonist JNJ7777120[1].
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