CAS No. : 102783-51-7
(Synonyms: dCTP (disodium); 2′-Deoxycytidine-5′-triphosphate (disodium))
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| Cat. No. : | HY-W010771 |
| M.Wt: | 511.12 |
| Formula: | C9H14N3Na2O13P3 |
| Purity: | >98 % |
| Solubility: | H2O : 125 mg/mL (ultrasonic) |
Deoxycytidine triphosphate (dCTP; 2′-Deoxycytidine-5′-triphosphate) disodium is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing[1][2][3].
In Vitro:Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C[1].
Deoxycytidine triphosphate disodium is a phosphoethanolamine cytidylyltransferase substrate[2].
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