BAY 60-2770


CAS No. : 1027642-43-8

1027642-43-8
Price and Availability of CAS No. : 1027642-43-8
Size Price Stock
5mg $130 In-stock
10mg $230 In-stock
25mg $490 In-stock
50mg $880 In-stock
100mg $1580 In-stock
200 mg Get quote
500 mg Get quote
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Cat. No. : HY-113926
M.Wt: 623.63
Formula: C35H33F4NO5
Purity: >98 %
Solubility: DMSO : 16.67 mg/mL (ultrasonic)
Introduction of 1027642-43-8 :

BAY 60-2770 is a potent, selective, and orally active soluble guanylyl cyclase (sGC) activator. BAY 60-2770 increases the activity of sGC in a nitric oxide-independent manner. BAY 60-2770 shows antifibrotic effect[1][2]. In Vivo: BAY 60-2770 (0.1-0.3 mg/Kg; p.o.) attenuates liver fibrosis in two rat models[1].
BAY 60-2770 (1 mg/kg; p.o.; daily from the 10th to the 12th week) results in amelioration of bladder dysfunction in high-fat obese mice[2].

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