PSB-0788
CAS No. : 1027513-54-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $160 | In-stock |
| 25mg | $325 | In-stock |
| 50mg | $520 | In-stock |
| 100mg | $830 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-103165 |
| M.Wt: | 543.04 |
| Formula: | C25H27ClN6O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
PSB-0788 is a new selective high-affinity A2B antagonist with IC50 value of 3.64 nM and Ki value of 0.393 nM, respeactively. PSB-0788 can be used for the research for chronic inflammatory lung diseases[1].
IC50 & Target: IC50: 3.64 nM (A2BAdoR)[1].
Ki: 0.393 nM (human, A2B); >1000 nM (A3 human recombinant); 333 nM (A2A human recombinant); 1730 nM (A2A rat brain striatal membranes); 2240 nM (A1 human recombinant); 386 nM (A1 rat brain cortical membranes))[1].
In Vitro: PSB-0788 (compound 17) has high potency at the A2BAdoR with IC50 value of 3.64 nM[1].
PSB-0788 has good profile of affinity and selectivity (Ki: 0.393 nM (A2B human recombinant); >1000 nM (A3 human recombinant); 333 nM (A2A human recombinant); 1730 nM (A2A rat brain striatal membranes); 2240 nM (A1 human recombinant); 386 nM (A1 rat brain cortical membranes))[1].
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