A-943931
CAS No. : 1027330-97-7
| Size | Price | Stock |
|---|---|---|
| 1mg | $60 | In-stock |
| 5mg | $185 | In-stock |
| 10mg | $300 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-113936 |
| M.Wt: | 295.38 |
| Formula: | C17H21N5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
A-943931 is a potent and selective histamine H4 receptor (H4R) antagonist with pKi values of 4.6, 3.8 nM for human and rat H4R, respectively. A-943931 shows anti-inflammatory and antinociceptive efficacy[1][2].
In Vivo:A-943931 shows anti-inflammatory activity in zymosan-induced peritonitis in mice with the ED50s of 34, 33 µmol/kg for s.c. and i.p., respectively[2].
A-943931 (10, 30, 100 µmol/kg; i.p.) shows antinociceptive efficacy in inflammatory pain and neuropathic pain model in rats[2].
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