UGM-IN-2
CAS No. : 1027102-49-3
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| Cat. No. : | HY-113652 |
| M.Wt: | 519.18 |
| Formula: | C18H13Cl2IN2O2S |
| Purity: | >98 % |
| Solubility: |
UGM-IN-2 is a UGM inhibitor with a Kd of 20 μM. It binds to the UGM isoforms of K. pneumoniae (Klebsiella pneumoniae) and M. tuberculosis (Mycobacterium tuberculosis) and inhibits mycobacterial growth. UGM-IN-2 can be used in studies related to mycobacterial infections and tuberculosis[1]. In Vitro:UGM-IN-2 (the penultimate compound in Supplementary Document S12) is a UGM inhibitor. UGM, a flavin-dependent enzyme unique to microorganisms, catalyzes the ring isomerization of UDP‑Galp to UDP‑Galf. As a key enzyme in furanose galactose synthesis, it represents a potential target for anti-infective therapy[1].
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