Valbenazine


CAS No. : 1025504-45-3

(Synonyms: NBI-98854)

1025504-45-3
Price and Availability of CAS No. : 1025504-45-3
Size Price Stock
2mg $70 In-stock
5mg $135 In-stock
10mg $220 In-stock
25mg $420 In-stock
50mg $650 In-stock
100mg $950 In-stock
200mg $1300 In-stock
1g $2600 In-stock
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Cat. No. : HY-16771
M.Wt: 418.57
Formula: C24H38N2O4
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 1025504-45-3 :

Valbenazine (NBI-98854) is a vesicular monoamine transporter 2 (VMAT2) inhibitor with the Ki of 110-190 nM[1]. In Vitro: Valbenazine exhibits VMAT2 binding affinity in rat striatum and human platelets with Kis of 110 and 150 nM, respectively[1]. In Vivo: Valbenazine (10 mg/kg; orally) induces ptosis (primarily an adrenergic response) and increases plasma prolactin primarily a dopaminergic response in rats[1].

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