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Cat. No. : | HY-101190 |
M.Wt: | 805.95 |
Formula: | C38H51N3O12S2 |
Purity: | >98 % |
Solubility: | 10 mM in DMSO |
Volixibat (SHP626) is a highly selective, minimally absorbed, and competitive apical sodium-dependent bile acid transporter (ASBT) inhibitor. Volixibat has potential for treatment for non-alcoholic steatohepatitis (NASH)[1][2]. In Vivo: Volixibat (SHP626) (5-30 mg/kg; food intake; daily for 24 weeks) improves metabolic aspects and components of non-alcoholic steatohepatitis in Ldlr-/-.Leiden mice[1].
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