Volixibat


CAS No. : 1025216-57-2

(Synonyms: SHP626; LUM002)

1025216-57-2
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Cat. No. : HY-101190
M.Wt: 805.95
Formula: C38H51N3O12S2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1025216-57-2 :

Volixibat (SHP626) is a highly selective, minimally absorbed, and competitive apical sodium-dependent bile acid transporter (ASBT) inhibitor. Volixibat has potential for treatment for non-alcoholic steatohepatitis (NASH)[1][2]. In Vivo: Volixibat (SHP626) (5-30 mg/kg; food intake; daily for 24 weeks) improves metabolic aspects and components of non-alcoholic steatohepatitis in Ldlr-/-.Leiden mice[1].

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