Difelikefalin
CAS No. : 1024828-77-0
(Synonyms: CR-845; FE-202845)
| Size | Price | Stock |
|---|---|---|
| 5mg | $320 | In-stock |
| 10mg | $510 | In-stock |
| 25mg | $950 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-17609 |
| M.Wt: | 679.85 |
| Formula: | C36H53N7O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : ≥ 100 mg/mL |
Difelikefalin (CR-845) is a peripherally restricted and selective agonist of kappa opioid receptor (KOR). Difelikefalin produces anti-inflammatory effects and has the potential in modulating pruritus in conditions such as chronic kidney disease[1][2]. IC50 & Target:kappa opioid receptor (KOR)[1] In Vitro:Difelikefalin (CR-845; FE-202845) does not penetrate the blood-brain barrier. Difelikefalin does not bind to mu opioid receptors or any other receptors beside KORs[1].
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