5-Iodouridine
CAS No. : 1024-99-3
| Size | Price | Stock |
|---|---|---|
| 1g | $9 | In-stock |
| 5g | $19 | In-stock |
| 10g | $32 | In-stock |
| 25g | $79 | In-stock |
| 100g | $308 | In-stock |
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| Cat. No. : | HY-W011079 |
| M.Wt: | 370.10 |
| Formula: | C9H11IN2O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
5-Iodouridine is an iodine-containing pyrimidine nucleoside analog. 5-Iodouridine inhibits dihydroorotase with a Ki value of 340 µM. 5-Iodouridine significantly enhances the cell-killing effect of gamma irradiation. 5-Iodouridine can be used in the research of HSV-1 infection and leukemia[1][2][3].
IC50 & Target:Ki: 340 µM (dihydroorotase)[1]
In Vitro:5-Iodouridine inhibits dihydroorotase, with a Ki of 340 µM[1].
5-Iodouridine (3 mM) significantly enhances the killing effect of gamma-rays on Chinese hamster Don cells under acidic pH (5.4) conditions[2].
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