PCI-33380
CAS No. : 1022899-36-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $350 | In-stock |
| 10mg | $550 | In-stock |
| 25mg | $1200 | In-stock |
| 50mg | $1900 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-100335 |
| M.Wt: | 855.78 |
| Formula: | C46H52BF2N11O3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 50 mg/mL |
PCI-33380 is a fluorescent probe ( (Ex=532 nm, Em=555 nm). PCI-33380 consists of a (BTK) inhibitor PCI-32765 (HY-10997) attaching with a Bodipy-FL fluorophore via a piperazine linker. PCI-33380 binds predominantly to Btk in B cell lysates with cell permeable activity. PCI-33380 can be used for imaging live cancer cells such as non-Hodgkin lymphoma research[1][2]
IC50 & Target:BTK[1][2].
In Vitro:PCI-33380 binds to Btk could be detected by denaturing gel electrophoresis and fluorescent gel scanning[2].
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