DPCPX


CAS No. : 102146-07-6

(Synonyms: PD 116948)

102146-07-6
Price and Availability of CAS No. : 102146-07-6
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50mg $116 In-stock
100mg $171 In-stock
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Cat. No. : HY-100937
M.Wt: 304.39
Formula: C16H24N4O2
Purity: >98 %
Solubility: DMSO : 10 mg/mL (ultrasonic)
Introduction of 102146-07-6 :

DPCPX (PD 116948), a xanthine derivative, is a highly potent and selective Adenosine A1 receptor antagonist, with a Ki of 0.46 nM in 3H-CHA binding to A1 receptors in rat whole brain membranes[1][2][3]. IC50 & Target:Ki: 0.46 nM (3H-CHA binding to A1 receptors in rat whole brain membranes); 340 nM (3H-NECA binding to A2 receptors in rat striatal membranes)[2]. In Vivo:DPCPX (PD 116948) ( 0.1, 0.3 and 1.0 mg/kg i.v. ) produces significant dose-related increases (P<0.05) in urine volume and in urinary sodium, potassium and chloride excretion[3].

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