Isoprocurcumenol
CAS No. : 102130-90-5
| Size | Price | Stock |
|---|---|---|
| 1mg | $355 | In-stock |
| 5mg | $885 | In-stock |
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| Cat. No. : | HY-113599 |
| M.Wt: | 234.33 |
| Formula: | C15H22O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 2.4 mg/mL (ultrasonic;warming) |
Isoprocurcumenol is a guaiane type sesquiterpene, that can be isolated from Curcuma comosa. Isoprocurcumenol can activate EGFR signaling. Isoprocurcumenol increases the phosphorylation of ERK and AKT. Isoprocurcumenol promotes the proliferation of keratinocytes[1][2][3].
In Vitro: Isoprocurcumenol (10 μM, 0-1 h) increases the phosphorylation of ERK and AKT[3].
Isoprocurcumenol (0-200 μM, 24 or 48 h) induces the proliferation of keratinocytes HaCaT cells[3].
Isoprocurcumenol (1 μM, 1 h) increases the expression of genes related to cell growth and proliferation, such as c-fos, c-jun, c-myc, and egr-1, through activation of the EGFR signaling pathway[3].
Isoprocurcumenol induces cell recovery and wound healing[3].
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