AM580 (GMP)
CAS No. : 102121-60-8
(Synonyms: CD336 (GMP); NSC608001 (GMP); Ro 40-6055 (GMP))
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| Cat. No. : | HY-10475G |
| M.Wt: | 351.44 |
| Formula: | C22H25NO3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
AM580 (CD336) (GMP) is AM580 (HY-10475) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. AM580 is a selective RARα agonist[1][2][3][4]. In Vitro: AM580 (GMP) (0.05 μM) induces mouse embryonic fibroblasts (MEFs) convert into chemically induced pluripotent stem cells (CiPSCs) with the adding in stage I and stage II medium[1]. AM580 (GMP) (0-10 μM; 4 d) induces SH-SY5Y cells develop into neuron-like cells[2]. AM580 (GMP) shows powerful and selective cyto-differentiating effects on acute promyelocytic leukemia cells[3]. AM580 (GMP) (2.5 μM; 4 d) induces myeloid progenitors develop into neutrophils[4].
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