Esonarimod


CAS No. : 101973-77-7

(Synonyms: KE-298)

101973-77-7
Price and Availability of CAS No. : 101973-77-7
Size Price Stock
5mg $29 In-stock
10mg $44 In-stock
25mg $88 In-stock
50mg $133 In-stock
100mg $200 In-stock
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Cat. No. : HY-19440
M.Wt: 280.34
Formula: C14H16O4S
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 101973-77-7 :

Esonarimod (KE-298) is an antirheumatic agent. In Vitro: Esonarimod (KE-298) (10 to 300 μg/mL) suppresses the production of NO by RAW264.7 cells in a dose dependent manner. The IC50 of Esonarimod is 117.5 μg/mL. Esonarimod does not affect cellular viability at these tested doses. Esonarimod has no direct effect on NOS activity in cell-free extracts of RAW264.7 cells[1]. In Vivo: After repeated oral administration of Esonarimod (14C-KE-298), the radioactivity decreases rapidly and no tendency towards accumulation is found[2].

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