S0859
CAS No. : 1019331-10-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $66 | In-stock |
| 10mg | $110 | In-stock |
| 50mg | $429 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-15529 |
| M.Wt: | 530.04 |
| Formula: | C29H24ClN3O3S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
S0859 is a selective, high-affinity generic Na+/HCO3- transporter (NBC) inhibitor. S0859 reversibly inhibits NBC-mediated intracellular pH (pHi) recovery (Ki=1.7 μM, full inhibition at approximately 30 μM). IC50 & Target: NBC[1] In Vitro: Treatment with NBC inhibitor S0859 significantly increased caspase-3 activity and elevated the number of apoptotic EC. S0859 is potentially important for probing the transporter's functional role in heart and other tissues[1].
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