12-OAHSA
CAS No. : 101901-73-9
| Size | Price | Stock |
|---|---|---|
| 8.85 mM * 1 mL in Methyl acetate | $600 | In-stock |
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| Cat. No. : | HY-113878 |
| M.Wt: | 564.92 |
| Formula: | C36H68O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
12-OAHSA is a component of olive oil. 12-OAHSA has oral activity, and improves glucose homeostasis in insulin resistant obese mice[1].
In Vitro:12-OAHSA (25 μM, 24 h) inhibits LPS-induced IL-1b, IL-6, Nos2, and Tnf-α in Raw 264.7 macrophages[1].
12-OAHSA (25 μM, 6 h) reduces IKKβ phosphorylation and increases phosphorylation of p65 in Raw 264.7 macrophages[1].
In Vivo:12-OAHSA (30 mg/kg, p.o., for 10 d) inhibits obesity-induced insulin resistance in HFD induced obese C57BL/6 mice[1].
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