CVT-11127
CAS No. : 1018674-83-3
(Synonyms: GS-456332)
| Size | Price | Stock |
|---|---|---|
| 1mg | $119 | In-stock |
| 5mg | $250 | In-stock |
| 10mg | $350 | In-stock |
| 25mg | $600 | In-stock |
| 50mg | $900 | In-stock |
| 100mg | $1350 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-113638 |
| M.Wt: | 512.39 |
| Formula: | C25H23Cl2N5O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic) |
CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127 has the potential for the research of lung cancer[1].
IC50 & Target: SCD[1]
In Vitro: CVT-11127 (1 µM, 48 h) shows antiproliferation activity in H460 cells[1].
CVT-11127 (1 µM, 48 h) decreases the the population of cells in S-phase by 75%[1].
CVT-11127 (1 µM, 48 h) induces apoposis in H460 cells[1].
CVT-11127 (1, 2 µM) inhibitors the SCD (stearoylCoA desaturase) activity in H460 cells[1].
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