Fosdevirine


CAS No. : 1018450-26-4

(Synonyms: GSK2248761; FDV)

1018450-26-4
Price and Availability of CAS No. : 1018450-26-4
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1mg $195 Get quote
5mg $489 Get quote
10mg $713 Get quote
50 mg Get quote
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Cat. No. : HY-14891
M.Wt: 413.79
Formula: C20H17ClN3O3P
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1018450-26-4 :

Fosdevirine (GSK2248761) is is a potent, selective, non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1) replication with low nanomolar activity in vitro. Fosdevirine shows good activity against a broad range of HIV-1 strains, including efavirenz (HY-10572)-resistant clinical isolates[1]. In Vitro:Fosdevirine exhibits potent in vitro antiviral efficacy against K103N and Y181C single point mutations and was equally effective against most double mutants[1].

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