Trastuzumab emtansine


CAS No. : 1018448-65-1

(Synonyms: Ado-Trastuzumab emtansine; PRO132365; T-DM 1)

1018448-65-1
Price and Availability of CAS No. : 1018448-65-1
Size Price Stock
1mg $800 In-stock
5mg $1600 In-stock
10mg $2600 In-stock
25mg $4420 In-stock
50mg $6188 In-stock
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Cat. No. : HY-P9921
M.Wt: 1000.00
Formula: N/A
Purity: >98 %
Solubility: H2O
Introduction of 1018448-65-1 :

Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1 (HY-19792). Trastuzumab emtansine can be used for the research of advanced breast cancer[1][2]. In Vitro:Trastuzumab emtansine (2 μg/mL; 3 d) significantly inhibits the proliferation of epithelial ovarian cancer (EOC) cells[2]. In Vivo:Trastuzumab emtansine (15 mg/kg; i.v. three to five times weekly for 3 weeks) exhibits significantly anti-tumor effect in mice[2].

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