Trastuzumab emtansine (solution)
CAS No. : 1018448-65-1
(Synonyms: Ado-Trastuzumab emtansine (solution) ; PRO132365 (solution) ; T-DM 1 (solution))
| Size | Price | Stock |
|---|---|---|
| 1mg | $800 | In-stock |
| 5mg | $1600 | In-stock |
| 10mg | $2600 | In-stock |
| 25mg | $4420 | In-stock |
| 50mg | $6188 | In-stock |
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| Cat. No. : | HY-P9921A |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1 (derivative of maytansine), and the drug-linker conjugate for ADC is SMCC-DM1 (HY-101070). Trastuzumab emtansine can be used for the research of advanced breast cancer[1][2]. In Vitro: Trastuzumab emtansine (2 μg/mL; 3 d) significantly inhibits the proliferation of epithelial ovarian cancer (EOC) cells[2]. In Vivo: Trastuzumab emtansine (15 mg/kg; i.v. three to five times weekly for 3 weeks) exhibits significantly anti-tumor effect in mice[2].
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