Butenafine (Hydrochloride)


CAS No. : 101827-46-7

(Synonyms: KP363 (Hydrochloride))

101827-46-7
Price and Availability of CAS No. : 101827-46-7
Size Price Stock
500mg $66 In-stock
1g $106 In-stock
5g $317 In-stock
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Cat. No. : HY-17396
M.Wt: 353.93
Formula: C23H28ClN
Purity: >98 %
Solubility: H2O : 1 mg/mL (ultrasonic);DMSO : 25 mg/mL (ultrasonic)
Introduction of 101827-46-7 :

Butenafine Hydrochloride (KP363 Hydrochloride) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase. IC50 & Target:Antifungal; squalene epoxidase In Vitro: Butenafine Hydrochloride, a benzylamine derivative, is an antifungal which is used to control dermal fungal infections such as athletes foot and ring worm. Butenafine Hydrochloride is squalene epoxidase inhibitor, inhibits the synthesis of ergosterol needed in fungal cell membranes. The drug has excellent penetration into the epidermis and a prolonged retention time following topical application, conferring residual therapeutic activity after treatment cessation. Butenafine possess anti-inflammatory activity too. Butenafine hydrochloride 1% cream is safe and effective for tinea corporis cruris and tinea manuum pedis.

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