AX-9657
CAS No. : 1015439-77-6
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| Cat. No. : | HY-11046 |
| M.Wt: | 394.47 |
| Formula: | C22H26N4O3 |
| Purity: | >98 % |
| Solubility: |
KRP-109 is a neutrophil elastase (NE) inhibitor with activity in reducing lung inflammation. KRP-109 improves survival in mouse models and reduces the number of neutrophils and inflammation in the alveolar walls. KRP-109 significantly reduced cell and neutrophil counts in bronchoalveolar lavage fluid, as well as cytokine levels such as interleukin 1β and macrophage inflammatory protein 2. KRP-109 can be used in the research of severe pneumonia[1].
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