Tildacerfont


CAS No. : 1014983-00-6

(Synonyms: SPR001; LY2371712)

1014983-00-6
Price and Availability of CAS No. : 1014983-00-6
Size Price Stock
5mg $235 In-stock
10mg $366 In-stock
25mg $735 In-stock
50mg $1140 In-stock
100mg $1770 In-stock
250mg $3550 In-stock
500mg $5505 In-stock
1g $8533 In-stock
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10 g Get quote
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Cat. No. : HY-113603
M.Wt: 419.97
Formula: C20H26ClN5OS
Purity: >98 %
Solubility: DMSO : 10 mg/mL (ultrasonic)
Introduction of 1014983-00-6 :

Tildacerfont (SPR001; LY2371712) is an orally active, blood-brain barrier-penetrant selective corticotropin-releasing factor type 1 (CRF1) receptor antagonist. Tildacerfont selectively blocks CRF1 receptors, thereby inhibiting the release of pituitary adrenocorticotropic hormone (ACTH). Tildacerfont can be used in research related to congenital adrenal hyperplasia[1]. IC50 & Target:CRF1 receptor[1] In Vitro:Tildacerfont is a CRF1 receptor antagonist. Tildacerfont selectively blocks the CRF1 receptor and acts on the hypothalamic-pituitary-adrenal (HPA) axis[1].

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