Propargyl-PEG4-amine
CAS No. : 1013921-36-2
| Size | Price | Stock |
|---|---|---|
| 250mg | $19 | In-stock |
| 1g | $52 | In-stock |
| 5g | $239 | In-stock |
| 10g | $429 | In-stock |
| 25g | $858 | In-stock |
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| 100 g | Get quote | |
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| Cat. No. : | HY-114670 |
| M.Wt: | 231.29 |
| Formula: | C11H21NO4 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Propargyl-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-amine is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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