Valnemulin


CAS No. : 101312-92-9

101312-92-9
Price and Availability of CAS No. : 101312-92-9
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5mg $316 In-stock
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Cat. No. : HY-113829
M.Wt: 564.82
Formula: C31H52N2O5S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 101312-92-9 :

Valnemulin is an orally active broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria, anaerobic bacteria, Mycoplasma, and Spirochetes. Valnemulin ameliorates enteric diseases, acute polyarthritis and enzootic pneumonia in pigs[1]. Valnemulin exhibits anti-inflammatory efficacy against lipopolysaccharide (HY-D1056)-induced lung injury[2]. In Vitro:Valnemulin exhibits antimicrobial efficacy against Mycoplasma hyopneumoniae and Mycoplasma hyosynoviae, with MIC90s of 0.0005 μg/mL and 0.0001 to 0.00025 μg/mL, respectively[1]. In Vivo:Valnemulin (100 mg/kg, i.g., single dose) exhibits lung protectiv effects in LPS-induced acute lung injury in BALB/c mice[2].
Valnemulin hydrochloride (10 mg/kg, p.o.; 10 days) has a control effect in experimental infection of calves with Mycoplasma bovis, and can effectively eliminate Mycobacterium bovis in the lungs [3].

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