PI3Kα/mTOR-IN-1
CAS No. : 1013098-90-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $1526 | In-stock |
| 5 mg | Get quote | |
| 10 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-U00326 |
| M.Wt: | 310.35 |
| Formula: | C16H18N6O |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
PI3Kα/mTOR-IN-1 is a potent PI3Kα/mTOR dual inhibitor, with an IC50 of 7 nM for PI3Kα in a cell assay, and Kis of 10.6 nM and 12.5 nM for mTOR and PI3Kα in a cell free assay , respectively.
IC50 & Target: IC50: 7 nM (PI3Kα, cell)[1]
Ki: 10.6 nM (mTOR), 12.5 nM (Mouse PI3Kα)[1]
In Vitro: PI3Kα/mTOR-IN-1 exhibits potent activity against PI3Kα and mTOR, high LipE, good kinase selectivity and robust ADMET properties[1].
In Vivo: PI3Kα/mTOR-IN-1 exhibits low HLM ER, but it is highly cleared in rat liver microsome (RLM) with ER of 0.88. PI3Kα/mTOR-IN-1 exhibits moderate clearance, moderate Vdss, T1/2 of 0.9 h, and good oral bioavailability[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- PI3Kα/mTOR-IN-1
- Cat. No.:
- HY-U00326
- Quantity:
Your information is safe with us.