Lydimycin
CAS No. : 10118-85-1
(Synonyms: NSC 127473; U 15965; α-DHB; α-Dehydrobiotin)
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| Cat. No. : | HY-105801 |
| M.Wt: | 242.29 |
| Formula: | C10H14N2O3S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Lydimycin is a naturally occurring biotin analogue isolated from Streptomyces lydicus, with antibiotic property. IC50 & Target: Bacterial[1] In Vitro: Lydimycin (alpha-dehydrobiotin) is a naturally occurring biotin analogue, with antibiotic property. Lydimycin competes with biotin for the fixation on the apocarboxylases, producing irreversibly inactive enzymes[1]. Lydimycin (alpha-dehydrobiotin) acts as a biotin antimetabolite, and inhibits the synthesis of 7,8-diaminopelargonic acid aminotransferase and the dethiobiotin synthetase enzymes at 1 μg/mL[2].
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