Biotin-PEG2-C4-alkyne
CAS No. : 1011268-28-2
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| Cat. No. : | HY-113828 |
| M.Wt: | 468.61 |
| Formula: | C22H36N4O5S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Biotin-PEG2-C4-alkyne is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Biotin-PEG2-C4-alkyne is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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