Desethyl KBT-3022
CAS No. : 101001-72-3
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| Cat. No. : | HY-U00039 |
| M.Wt: | 420.48 |
| Formula: | C23H20N2O4S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Desethyl KBT-3022 is the main active metabolite of the new antiplatelet agent, KBT-3022. In Vitro: Pretreatment with desethyl KBT-3022 0.1, 0.3 and 1 mg/kg, i.v. prolongs the time required to achieve thrombotic occlusion in the femoral artery and inhibits collagen-induced platelet aggregation in whole blood ex vivo, each in a dose-dependent manner. Desethyl KBT-3022 inhibits the thrombin-induced aggregation of washed platelets in a concentration-dependent manner 1–40 μM[1].
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