Phenacaine


CAS No. : 101-93-9

(Synonyms: Holocaine)

101-93-9
Price and Availability of CAS No. : 101-93-9
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Cat. No. : HY-B1726
M.Wt: 298.38
Formula: C18H22N2O2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 101-93-9 :

Phenacaine (Holocaine) is a local agent that can suppress or relieve pain. Phenacaine inhibits the specific calmodulin-dependent stimulation of erythrocyte Ca2+-ATPase and cyclic nucleotide phosphodiesterases from brain and heart[1][2]. In Vitro:Phenacaine inhibits the specific calmodulin-dependent stimulation of erythrocyte Ca2+-ATPase (EC 3.6.1.3) and cyclic nucleotide phosphodiesterase (EC 3.1.4.17) in brain and heart tissues[1].
Phenacaine (1 μM-1 mM) depresses glucose-induced insulin secretion by pancreas[2].

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