NADPH (tetracyclohexanamine)


CAS No. : 100929-71-3

100929-71-3
Price and Availability of CAS No. : 100929-71-3
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10mg $25 In-stock
25mg $45 In-stock
50mg $60 In-stock
100mg $96 In-stock
250mg $221 In-stock
500mg $377 In-stock
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Cat. No. : HY-F0003A
M.Wt: 1142.12
Formula: C45H82N11O17P3
Purity: >98 %
Solubility:
Introduction of 100929-71-3 :

NADPH tetracyclohexanamine functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetracyclohexanamine is an endogenous inhibitor of ferroptosis. NADPH tetracyclohexanamine plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication[1][2][3][4]. In Vitro:The regeneration rate of NADPH tetracyclohexanamine is often the rate-limiting step for the over-production of desired chemicals, while maintaining robust cellular growth[2].
NADPH tetracyclohexanamine homeostasis is regulated by varied signaling pathways and several metabolic enzymes that undergo adaptive alteration in cancer cells. The metabolic reprogramming of NADPH tetracyclohexanamine renders cancer cells both highly dependent on this metabolic network for antioxidant capacity and more susceptible to oxidative stress[3].
NADPH tetracyclohexanamine is an essential intracellular reductant needed to eliminate lipid hydroperoxides. Indeed, NADPH tetracyclohexanamine levels are a biomarker of ferroptosis sensitivity across many cancer cell lines[4].

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