MX69
CAS No. : 1005264-47-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $70 | In-stock |
| 10mg | $120 | In-stock |
| 25mg | $220 | In-stock |
| 50mg | $350 | In-stock |
| 100mg | $550 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-100892 |
| M.Wt: | 474.57 |
| Formula: | C27H26N2O4S |
| Purity: | >98 % |
| Solubility: | H2O : < 0.1 mg/mL;DMSO : 100 mg/mL (ultrasonic) |
MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment. In Vitro: MX69 blocks the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation. MX69 shows minimal inhibitory effect on normal human hematopoiesis in vitro and is very well tolerated in animal models. MX69-induced MDM2 downregulation results not only in inhibition of XIAP expression, but also in activation of p53, which contributes to cancer cell apoptosis in vitro[1]. In Vivo: MX69-induced MDM2 downregulation results in activation of p53 which contributes to inhibition of cancer cell proliferation in vivo[1].
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