TCS2002
CAS No. : 1005201-24-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $408 | In-stock |
| 10mg | $653 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-10096 |
| M.Wt: | 338.38 |
| Formula: | C18H14N2O3S |
| Purity: | >98 % |
| Solubility: | DMSO : 34 mg/mL (ultrasonic;warming) |
TCS2002 (Compound 9b) is a highly selective, orally bioavailable and potent GSK-3β inhibitor with the IC50 of 35 nM. TCS2002 shows good pharmacokinetic profiles including favorable BBB penetration. TCS2002 can be used for the research of Alzheimer’s disease[1]. In Vivo:TCS2002 (Compound 9b) (1-3 mg/kg;1-24 hours; GS rats andC57BL/6N mice) exhibits good pharmacokinetic profiles and favor able BBB permeability with AUC0-24h value is 734 ng h/g and Kp value (ratio of brain and plasma) is 1.6[1].
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