Sodium Picosulfate


CAS No. : 10040-45-6

(Synonyms: Sodium Picosulphate)

10040-45-6
Price and Availability of CAS No. : 10040-45-6
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50mg $56 In-stock
100mg $90 In-stock
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Cat. No. : HY-B0544
M.Wt: 481.41
Formula: C18H13NNa2O8S2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic);H2O : ≥ 100 mg/mL
Introduction of 10040-45-6 :

Sodium Picosulfate (Sodium Picosulphate) is a contact irritant laxative with oral activity. Sodium Picosulfate inhibits the absorption of water and electrolytes, increasing their production. Sodium Picosulfate can be used in colonoscopy applications[1][2][3][4]. In Vitro:Sodium Picosulfate (400, 800, 1600 μg/mL) has different toxicity to rabbit, rat and human hepatocytes, and rat hepatocytes are the best tolerated[1].
In Vivo:Sodium Picosulfate (10 mg/kg, dissolved in 0.3% tragacanth in water, intragastric administration) has no significant effect on the proliferation of epithelial cells in the ileum and colon of rats[2].
Sodium Picosulfate (2.5, 10 mg/kg/day, dissolved in 0.5% tragacanth gum, intragastric administration) does not cause chronic changes in colon movement in rats[3].

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