Crolibulin
CAS No. : 1000852-17-4
(Synonyms: EPC2407)
| Size | Price | Stock |
|---|---|---|
| 5mg | $141 | In-stock |
| 10mg | $211 | In-stock |
| 25mg | $380 | In-stock |
| 50mg | $551 | In-stock |
| 100mg | $800 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-13603 |
| M.Wt: | 417.26 |
| Formula: | C18H17BrN4O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic;warming) |
Crolibulin (EPC2407) is a tubulin polymerization inhibitor, with potent apoptosis induction and cell growth inhibition. Crolibulin has anti-tumor activity. Crolibulin also has cardiovascular toxicity and neurotoxicity[1][2][3].
IC50 & Target: Tubulin polymerization[1]
In Vitro: Crolibulin shows significant cytotoxic activity against HT-29 cells, with an IC50 of 0.52 μM[2].
Crolibulin is active against various experimental tumors and exhibit potent inhibition of mitosis at the G2/M stage[2].
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