Tilapertin
CAS No. : 1000690-85-6
(Synonyms: AMG747)
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| Cat. No. : | HY-19887 |
| M.Wt: | 378.39 |
| Formula: | C20H21F3N2O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Tilapertin is an oral inhibitor of glycine transporter type-1 (GlyT1). IC50 & Target: GlyT1[1] In Vivo: Tilapertin is a nanomolar potent, orally bioavailable and selective GlyT1 inhibitor. Oral administration of Tilapertin dose-dependently increases cerebrospinal fluid (CSF) glycine concentration in rats[1].
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