3-Hydroxybenzaldehyde
CAS No. : 100-83-4
(Synonyms: M-Hydroxybenzaldehyde)
| Size | Price | Stock |
|---|---|---|
| 5g | $12 | In-stock |
| 25g | $22 | In-stock |
| 100g | $25 | In-stock |
| 500g | $68 | In-stock |
| 1000g | $126 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-76006 |
| M.Wt: | 122.12 |
| Formula: | C7H6O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
3-Hydroxybenzaldehyde (3-HBA) is a precursor compound for phenolic compounds like Protocatechuic aldehyde (PCA) (HY-N0295). 3-Hydroxybenzaldehyde, produced by 3-hydroxybenzyl-alcohol dehydrogenase, is a substrate of aldehyde dehydrogenase (ALDH) in rats and humans. 3-Hydroxybenzaldehyde has vasculoprotective effects in vitro and in vivo. 3-Hydroxybenzaldehyde is proming for research of atherosclerosis[1][2][3][4].
IC50 & Target:IC50: substrate of aldehyde dehydrogenase (ALDH)[1]
In Vitro:3-Hydroxybenzaldehyde (0-100 μM, 24 h) inhibits vascular smooth muscle cells (VSMC) proliferation, cell cycle and cell migration[1].
3-Hydroxybenzaldehyde (100 μM, 25 h) inhibits production levels of p-NF-κB and p-p38 increased by TNF-α in human umbilical vein endothelial cells (HUVECs)[1].
In Vivo:3-Hydroxybenzaldehyde (100 mg/kg, i.p., daily for 1 week) inhibits angiogenesis and exhibits anti-thrombic effects ex vivo and in vivo[1].
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